In this study, the spherical molybdenum powder with high density and low oxygen content for 3Dprinting was prepared by plasma spheroidization and hydrogen reduction, and the material properties of sphericalmolybdenum powder were tested and analyzed. The spherical molybdenum powder for 3D printing with highdensity was prepared by adjusting the power, powder feeding amount and gas flow rate in the plasma process.Meanwhile, the hydrogen reduction has been adopted to reduce the oxygen content of the spherical molybdenumpowder. Compared to the original powder, and the apparent density of the molybdenum powder increased from 2.3g/cm3 to 6.01 g/cm3, the flowability increased from 35s/50 g to 10.5 s/50 g and the oxygen content reached 270 ppm.